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KMID : 1207720090010020090
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Clinics in Orthopedic Surgery
2009 Volume.1 No. 2 p.90 ~ p.95
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Contribution of the Proximal Nerve Stump in End-to-side Nerve Repair: In a Rat Model
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Jung Jun-Mo
Chung Moon-Sang
Kim Min-Bom
Baek Goo-Hyun
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Abstract
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Background: The aim of this study was to evaluate the contribution of the proximal nerve stump, in end-to-side nerve repair, to functional recovery, by modifying the classic end-to-side neurorrhaphy and suturing the proximal nerve stump to a donor nerve in a rat model of a severed median nerve.
Methods: Three experimental groups were studied: a modified end-to-side neurorrhaphy with suturing of the proximal nerve stump (double end-to-side neurorrhaphy, Group I), a classic end-to-side neurorrhaphy (Group II) and a control group without neurorrhaphy (Group III). Twenty weeks after surgery, grasping testing, muscle contractility testing, and histological studies were performed.
Results: The grasping strength, muscle contraction force and nerve fiber count were significantly higher in group I than in group II, and there was no evidence of nerve recovery in group III.
Conclusions: The contribution from the proximal nerve stump in double end-to-side nerve repair might improve axonal sprouting from the donor nerve and help achieve a better functional recovery in an end-to-side coaptation model
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KEYWORD
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Median nerve, Proximal stump, Peripheral nerve injury, End-to-side neurorrhaphy, Nerve recovery
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